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Neonatal jaundice

"HOT BILE"

Frequent causes of unconjugated neonatal jaundice:

Hereditary sphaerocytosis
Obstruction of bowel
Thalassaemia alpha
Blood group incompatibility
Infection
Lucey-Discroll syndrome
Enzyme deficiency (G6PD,PK)

Frequent causes of haemolytic neonatal jaundice at 24 hours of age:

RAGS

Rhesus incompatibility
ABO incompatibility
G6PD deficiency
Spherocytosis

Frequent causes of neonatal jaundice caused by increased bilirubin production):

FIRST

Feto maternal blood incomptability e.g. Rh or ABO
Infections, Increased enterohepatic circulation (large bowel obstruction)
Red Cell enzymopathies: (G6PD or Pyruvate kinase deficiency)
Spherocytosis hereditary
Thalassemia alpha

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