SLE: Signs and symptoms, diagnostic criteria

According to the guidelines of American College of Rheumatology a person can be diagnosed to have SLE if any 4 out of the11 symptoms are present simultaneously or serially on two seperate occasions.
' SOAP BRAIN MD'

• Serositis  (pleuritis, pericarditis)
• Oral ulcers
• Arthritis  (2 or more peripheral joints)
• Photosensitivity
• Blood changes  (anemia, leukopenia, thrombocytopenia-ie., a fall in all parameters )
• Renal involvement (persistent proteinuria>0.5g/day or cellular casts-due to immune complex deposition in kidney)
• ANA +   (detected by immunofluorescence)
• Immunologic changes (Antibodies against double-stranded DNA,Sm antigen)
• Neurologic  (seizures,psychosis)
• Malar rash
• Discoid rash.