Neurofibromatosis type 1: features

"CAFE SPOT" :

• Café au lait spots
• Axillary freckling
• Fibromatosis
• Eye- Lisch nodules

• Skeletal bowing
• Positive family history
• Optic Tumor

Neurofibromatosis type I (NF-1) is a tumor disorder that is caused by the malfunction of a single gene on chromosome 17.