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Receptors of the heart

Think: "2 Beautiful hearts Marry 2 B1"
  • B receptor (adrenergic)
  • M receptor (cholinergic) and
  • B receptor (adrenergic)

The heart is innervated by both sympathetic (adrenergic) and parasympathetic (cholinergic) fibres.
Adrenergic nerves from cervical sympathetic chain exerts positive ionotropic (contractility) and chronotropic (heart rate) effects on heart through B1 receptors.
B2 receptors are more in smooth muscles of vessel walls and thus mediate vasodilatation.
Parasympathetic fibres which reach the heart through the vagus nerves have inhibitory effect on the heart through M2 receptors and is responsible for decreasing heart rate, conduction (dromotropic) and contractility.

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